Three Points You Cannot Ignore in Membranous Nephropathy

Three Points You Cannot Ignore in Membranous NephropathyAccording to statistics, Membranous Nephropathy accounts for nearly one third of all glomerular diseases, and its incidence has been increasing every year in the past decade. In this article, let’s have a quick look at this disease.

Membranous Nephropathy has three advantages in treatment.

1. Easy to cure

The main manifestations are as follows: nearly 30% of the patients, mostly young patients, do not need steroids and other drugs after onset, and it can get into remission spontaneously within 2 years; the disease is more sensitive to steroid treatment. Even if it can not be relieved, the cure rate of adhering to steroid combined with immunosuppressive drugs is relatively high.

2. Low relapse rate

For the patients taking steroids and immunosuppressive agents, after the treatment of eliminating inflammation and reducing proteinuria, the condition can be maintained stable and the recurrence rate is relatively low.

3. No renal biopsy is required for diagnosis

Renal biopsy is one of the most commonly used examinations for the diagnosis of pathological types of kidney disease at present, but membranous nephropathy is an exception and can be diagnosed without needing renal biopsy.

Idiopathic membranous nephropathy is mostly associated with anti-phospholipase A2 receptor antibodies. Antiphospholipase A2 receptor antibodies bind to corresponding antigens on podocytes, forming in situ immune complexes, damaging podocytes, destroying glomerular filtration barriers and producing proteinuria. Membranous nephropathy can be determined by examining anti-phospholipase A2 receptor antibodies.

In addition to the advantages of membranous nephropathy itself, these three key points are also very important in its treatment.

1. To apply steroid + immunosuppressant correctly

In the course of treatment, kidney patients should adhere to the principle of starting with adequate dosage and gradually reducing dosage of steroids. After 6-8 weeks of taking steroids in sufficient dosage, the dosage can be gradually reduced according to the amount of proteinuria, but in order to maintain the stability of renal function, you should adhere to taking drugs for at least one year, then gradually reducing dosage and stopping medication. At the same time, we can choose Traditional Chinese Medicine Treatment such as Moxibustion to improve blood condition, stabilize the illness condition and inhibit the recurrence of inflammation.

2. To improve immunity, prevent infection, fatigue and other factors

Although membranous nephropathy is not easy to recur after treatment, we should also pay attention to some inducing factors, such as repeated infection, overwork, smoking and so on, which lead to the decline of immunity and the recurrence of proteinuria. In the usual checkups, you should pay attention to the detection of immunoglobulin and other reactive immunity indicators.

3. To adhere to a low amount of high-quality diet, and balanced nutrition

In order to cooperate with the use of steroids and immunosuppressive agents and reduce the metabolic burden of kidneys, kidney patients should adhere to the principle of a low amount of high-quality protein diet. On the one hand, it can prevent the increase of protein leakage; on the other hand, it can avoid malnutrition. Daily food containing high-quality protein, such as meat, eggs, milk, soybean products, etc., is the best combination to take.

Now you have a clear mind about Membranous Nephropathy. For more information on kidney disease, please leave a message below or contact online doctor.


***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***

Share Link

Leave A Message

Hope the above information is helpful for you. If you have any questions on it, you can leave a message below. We have doctors to contact you and give you free online guidance.