Does Normal Creatinine Level Mean Kidneys Are Healthy
Does normal creatinine level mean kidneys are healthy?
Creatinine is the metabolic product of muscle in human body, which is mainly filtered out by glomeruli. 1 mg of creatinine can be produced by every 20 g of muscle metabolism. When the intake of meat is stable and there is no significant change in muscle metabolism, creatinine production will be relatively constant.
About serum creatinine
Clinical test of serum creatinine is one of the main methods to understand renal function.
Endogenous creatinine is the product of muscle metabolism. In muscle, creatine slowly forms creatinine through irreversible non-enzymatic dehydration, which is released into the blood and excreted with urine. Therefore, serum creatinine is closely related to the total amount of muscle in the body and is not easily affected by diet. Creatinine is a small molecule substance, which can be filtered through the glomeruli. It is rarely absorbed in the renal tubules. The creatinine produced in the body every day is almost completely excreted with the urine and is generally not affected by the amount of urine.
When renal insufficiency occurs, creatinine accumulates in the body and becomes a harmful toxin to the human body. The normal upper limit of plasma creatinine is about 100 umol/L. And different hospital testing standards are different, but will not exceed 120 umol/L. Endogenous creatinine clearance rate (Ccr) is defined as the clearance of endogenous creatinine in several milliliters of plasma per unit time of the kidney. Endogenous creatinine clearance test can reflect glomerular filtration function and roughly estimate the number of effective nephron units, so it is a quantitative test to measure renal damage. Because of its simple operation, less interference factors and high sensitivity, it is one of the better renal function tests commonly used in clinic.
Does normal creatinine level mean there is no problem with kidneys?
Does a normal serum creatinine test mean that there is no problem? Serum creatinine is the most commonly used index to detect renal function. It is also a compulsory item for health examination.
Many of the inspected people, when their serum creatinine level is within the normal range, think that their kidney function is completely okay. In fact, this is a misunderstanding of serum creatinine value. Because serum creatinine can not reflect the status of renal function in time and accurately. When most of the human kidneys suffer from pathological damage and the glomerular filtration rate decreases by a large proportion (more than 50%), the increase of serum creatinine may be seen in clinical practice. Therefore, the misunderstanding that the serum creatinine level is normal, indicating that the kidney is okay should be corrected. If you have vegetarian diet or leaner small muscle size, serum creatinine value can be low, and then you need to strengthen nutrition.
Now you know that when your creatinine level is normal, it does not mean your kidneys are ok. Besides serum creatinine level, you should pay attention to other tests, such as urea test, 24h urine protein test, urine routine test, etc. For more information on high creatinine level, please leave a message below or contact online doctor.
***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***