When Is the Best Time to Take Hypoglycemic Drugs

When Is the Best Time to Take Hypoglycemic DrugsEvery diabetic may have different prescriptions, so the time of medication should vary from person to person. So, when is the best time to take hypoglycemic drugs for Diabetes patients?

On an empty stomach in the morning

Insulin sensitizers, such as rosiglitazone and pioglitazone, can increase the sensitivity of tissue cell receptors to insulin, effectively utilize self-secreted insulin, so that glucose can be utilized by cells as soon as possible, and blood sugar can be lowered.

Its hypoglycemic effect can be maintained for 24 hours, so it is only taken once a day.

Thiazolidinediones begin to take effect 30 minutes after oral administration and reach the peak concentration in blood two hours after oral administration. The peak concentration of thiazolidinediones in blood will be delayed by 3 to 4 hours when taking food. Therefore, thiazolidinediones are generally suitable for taking in the morning on an empty stomach.

Half an hour before meal

Sulfonylurea hypoglycemic drugs, including glibenclamide, gliclazide, glipizide, gliquidone, etc.. They mainly play a role by stimulating insulin secretion by islet beta cells.

Most sulfonylurea hypoglycemic drugs take half an hour to take effect, and the peak of hypoglycemic effect usually occurs 2-3 hours after taking the medicine.

That is to say, it takes more than half an hour after taking hypoglycemic drugs before they begin to exert hypoglycemic effect, and the effect is strongest in 2-3 hours after taking drugs.

Therefore, take sulfonylureas 30 minutes before meals.

5-20 minutes before meals

Non-sulfonylurea insulin secretagogues, include repaglinide, nateglinide and so on.

The premise of its action is the existence of glucose, so it can stimulate the secretion of pancreatic beta cells only when it works at meals.

It is also an insulin secretagogue, but it should be taken orally 5 to 20 minutes before meals because it works faster than sulfonylureas. If not taken on time, it may cause hypoglycemia.

Chew at the same time as the first bite of meal

Alpha-glucosidase inhibitors, such as acarbose, need to be taken with the first bite of meal and chewed, which can delay and reduce the decomposition of carbohydrates into glucose in the small intestine and reduce postprandial blood sugar levels.

This medicine has the best chewing effect with the first bite of meal, and the diet must contain certain carbohydrates (such as rice, flour, etc.) before it can work.

If taken after meals or before meals, it will not have the effect of reducing blood sugar.

After meal

Metformins should be taken after meals because they can irritate the gastric mucosa and cause stomach discomfort.

When is the best time to take hypoglycemic drugs? Now you get the answer. For more information on diabetes treatment, please leave a message below or contact online doctor.


***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***

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