How to Choose Lipid-Lowering Drugs for Diabetic Patients
How to choose lipid-lowering drugs for diabetic patients?
Diabetic patients often have hyperlipidemia, which is the primary cause of atherosclerosis so as to lead to coronary heart disease and cerebrovascular accident. It is also the main risk factor that threatens the health and life of diabetic patients. Studies have found that a 10% reduction in plasma total cholesterol and a 10% increase in high density lipoprotein can reduce the mortality rate of coronary heart disease by 2%. Therefore, lipid-lowering drugs are needed to help prevent chronic complications such as vascular sclerosis.
We know that there are two kinds of lipid-lowering drugs currently used in clinical practice: statins (such as Lipitor, Zocor) and fibrates (Lipanthyl). Statins are mainly aimed at low density lipoprotein (cholesterol) and also have the effect of moderate reduction of triglycerides. Fibrates is mainly aimed at triglycerides.
How to choose lipid-lowering drugs? You should follow these principles.
For patients with significant hypertriglyceridemia, including after statin use, low density lipoprotein cholesterin (LDL-C) has reached the target, while non-HDL-C other than LDL-C has not yet reached the target, fenofibrate may be considered as an additional drug.
According to the 2013 edition of the Chinese Diabetes Guidelines and the 2015 edition of the American Diabetes Association (ADA) Guidelines, if the triglyceride (TG) of diabetic patients is more than 5.7 mmol/L, fibrate drugs should be used first to reduce the risk of pancreatitis.
In 2013, fenofibrate was approved in Australia as a new indication for diabetic retinopathy to reduce disease progression in type 2 diabetic patients with diabetic retinopathy, but it cannot replace proper blood pressure, blood sugar and lipid control.
Therefore, lipid reduction is not only dependent on statins, but also needs to be adjusted or combined according to the situation.
And besides medication, you should adjust your lifestyle actively to help lower lipid level.
1. Dietary therapy: light, low-fat, low-sugar diet, eat more fish, fresh melons and fruits, black fungus, garlic, tea, eat less animal viscera, fried food, nuts and other foods with high cholesterol content.
2. Drink plenty of water: blood concentration, increased blood viscosity, and slowed flow rate, promote platelet deposition in the local, easy to form thrombus. Drinking more water helps to dilute blood and relieve blood viscosity.
3. Proper selection of soybean food: soybean is rich in lecithin, which is conducive to the use of lipids through blood vessel wall for tissue. It can reduce cholesterol in blood, improve blood viscosity and avoid cholesterol deposition in blood vessel.
4. Strengthen exercise: Exercise can enhance the activity of protease, enhance high-density lipoprotein, reduce triglyceride, cholesterol and low-density lipoprotein cholesterol, and help to consume calories, maintain blood sugar and weight stability.
5. Quit smoking and alcohol: Smoking can lead to the decrease of high density lipoprotein, stimulate the secretion of adrenaline, accelerate the secretion of fat, resulting in the rise of fatty acids and low density lipoprotein, so people with high blood cholesterol should quit smoking.
How to choose lipid-lowering drugs for diabetic patients? Now you get the answer. For more information on Diabetes treatment, please leave a message below or contact online doctor.
***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***