Why Are Dialysis Patients Prone to Skin Itching
With the continuous development of blood purification technology, more and more uremic patients have been treated effectively, their survival time is longer and longer, and Dialysis-related complications continue to occur. Skin itching is one of the common complications. The incidence of skin itching in maintenance dialysis patients is as high as 50%-90%. It is a systemic disease rather than a simple skin disease, which seriously affects the quality of life of patients. It not only interferes with their sleep and work, but also causes skin infection, skin damage and other symptoms. In order to alleviate the itching and improve the quality of life of maintenance dialysis patients, it is necessary to carry out health education in this respect for maintenance dialysis patients.
The influencing factors of skin itching are clarified from the following aspects:
1. Dry skin and lack of water
Because of atrophy of sebaceous glands and sweat glands, dysfunction of exocrine secretion and increase of pH in cuticle, the skin of hemodialysis patients is dry. At the same time, the excess water in the body of uremic patients is removed by hemodialysis. The imbalance of water in skin cells during and after primary dialysis is particularly obvious. At this time, itching is more serious.
2. Toxin accumulation
Although dialysis can remove some toxins from uremic patients, it can not completely replace the detoxification function of the kidney. Conventional hemodialysis can only remove small molecule toxins and water, and its removal effect of large and medium molecule toxins is not ideal. Patients often have hypercalcemia, hypermagnesemia and hyperphosphorus due to the increase of bivalent ions, which will promote the accumulation of medium molecule toxins, and then cause severe skin itching. In addition, the susceptibility and severity of skin itching are positively correlated with serum creatinine and urea levels.
3. Allergic reaction
Dialysis process increases the contact between patients and allergenic substances, such as disinfected iodine, alcohol, adhesive, dialyzer, dialysis blood pipeline, ethylene oxide contained in puncture needle, residual peracetic acid disinfectant contained in reuse dialyzer and so on, which can stimulate mast cell proliferation and trigger allergic reaction.
Inadequate dialysis often causes nausea, vomiting, loss of appetite, etc. Long-term low nutrient intake will lead to negative nitrogen balance in patients. The nutritional ingredients needed by the skin are deficient, and the cutin of the skin is obvious and the sensitivity is increased.
Uremic patients are often accompanied by hyperparathyroidism. High concentration of PTH in blood can stimulate skin mast cells to release histamine, promote the deposition of calcium and magnesium ions in the skin and cause skin itching. Meanwhile, PTH is a medium and macromolecule substance with low plasma concentration and low concentration gradient. The effect of diffusion clearance is poor, so the clearance rate of dialysis alone is low, which can easily lead to pruritus.
6. Personal hygiene
Uremic patients have poor physique and are prone to cold. Patients with catheterization are inconvenient to move or dare not bathe or change underwear. The use of underwear and bed sheets containing chemical fibers causes itching of the skin.
7. Basic diseases
Uremic patients are often accompanied by other diseases, such as Diabetes mellitus, which can make uremic patients accumulate toxin molecules, causing itching.
Why are dialysis patients prone to skin itching? Now you have a clear mind. For more information on dialysis, please leave a message below or contact online doctor.
***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***