5 Early Symptoms Of Nephrotic Syndrome Relapse
Nephrotic syndrome is a group of clinical syndromes characterized by a variety of causes, including massive proteinuria (> 3.5g /24h), hypoproteinemia (< 30 g/L), hyperlipidemia, and edema.
Common symptoms of Nephrotic Syndrome
According to the etiology, it can be divided into primary, secondary and hereditary categories. Diagnosis for primary NS needs to exclude secondary and hereditary NS, such as Alport syndrome, congenital nephrotic syndrome, Finnish type, hormone resistant NS, and hereditary amyloidosis.
What are early symptoms of Nephrotic Syndrome relapse?
1. Increased bubbles in urine
When nephrotic syndrome recurs, the protein in urine is increased, which is easy to breed bacteria. Bacteria will destroy the composition and structure of urine, resulting in excessive bubbles in urine. The surface tension of protein is low, and the surface of urine will naturally form bubbles.
2. Poor appetite
When nephrotic syndrome relapses, swelling in intestinal mucosa will cause poor appetite of patients.
When Nephrotic Syndrome relapses, since patients have poor appetite, insufficient protein intake and absorption, protein leaks into urine, resulting in hypoproteinemia.
4. Eyelid and lower limb swelling
When nephrotic syndrome relapses, it forms hypoproteinemia, water and sodium retention, eyelid and lower limb edema.
When Nephrotic Syndrome relapses, since protein leaks and liver synthesis lipoprotein increases while catabolism obstacle forms hyperlipidemia.
Common complications of Nephrotic Syndrome
Infection is the most common complication and often associated with the massive loss of immunoglobin in urine, immune dysfunction, malnutrition, hormone and cytotoxic drug use.
2. Thrombosis and embolism
The change of hematoma coagulation factor, the use of hormones and diuretics and blood viscosity from hyperlipidemia are the causes of hypercoagulability and venous thrombosis. Renal vein and lower limb vein thrombosis are common.
3. Acute kidney injury
Effective circulating blood volume deficiency leads to decreased blood flow and prerenal azotemia, which is more likely to occur when patients with nephrotic syndrome with severe edema are given powerful diuretic treatment.
4. Disorder of metabolism of protein and fat
Long-term hypoalbuminemia can cause malnutrition, decreased body resistance, growth retardation, endocrine disorders, etc. It can also lead to a decrease in the binding of drug to proteins, an increase of free drugs, affect the efficacy of drugs and increase the toxic effects of some drugs.
Hormones and immunosuppressant agents only control Nephrotic Syndrome temporarily. To avoid the relapse, we recommend a systematic Chinese medicine treatments including Micro-Chinese Medicine Osmotherapy, Medicated Bath, Medicated Foot Bath, Mai Kang Mixture, Steaming Therapy, Enema Therapy and Moxibustion Therapy, etc. They can repair injured glomeruli and improve renal function to avoid relapse of Nephrotic Syndrome. If you want to learn more information, you can leave a message below or consult our online doctor directly.
***Please seek professional medical advise for the diagnosis or treatment of any ailment, disease or medical condition. This article is not intended to be a substitute for the advice of a licensed medical professional.***